Research project

Design and characterization of a multimodal photostimulation system (MITACS with Bliq Photonique)

Description

We are looking for a graduate student or post-doctoral fellow for a Mitacs internship in Antoine Godin's group in collaboration with Bliq Photonique, a dynamic young company. Antoine Godin's research program, a Sentinel North Partnership Research Chair, trains highly qualified researchers at the frontiers of photonics, nanotechnology, mathematics and neuroscience. Its research uses cutting-edge methodological approaches and offers new insights into the functioning of the brain and its diseases. Bliq Photonique is part of the photonic optics industrial cluster, a group of companies that promotes innovative, cutting-edge technologies and is internationally renowned in the Quebec City region. Bliq Photonique's mission is to provide the most useful microscopy systems for in vivo imaging from Quebec City to researchers around the world.

The project presented here consists in designing a photostimulation system integrating several excitation lasers and developing three independent and flexible excitation modules. The use of light to stimulate a sample can allow the activation (e.g. photoactivation, uncaging) of spatially localized regions (focal), or of much larger fields (wide field) with high temporal accuracies. Recently, deformable mirrors composed of several small rotating mirrors organized in a grid that may or may not reflect light, depending on their position/state, have been used in microscopy. A digital micromirror device (DMD) allowing to produce new illumination patterns with a high spatio-temporal resolution will be integrated in the photostimulation module.

This project consists of an integration of three distinct excitation modes and a thorough comparison of these modes for neuroscience applications. The ability to simultaneously stimulate using multiple modalities with different lasers and on distinct regions by modulating the excitation sequences (e.g., position, intensity, and frequency) independently is an option with strong innovative potential and will be tested during the internship. DMDs will offer a flexible option to generate illumination patterns on demand.

This Mitacs internship, at the CERVO research center, will focus on the integration, optimization and characterization of these three stimulation modules. During this project, the student or postdoctoral fellow will be exposed to the following techniques:
- Optical microscopy
- Fluorescence imaging at video rate
- Optogenetics
- Biophotonics
Internship Requirements:
- Experience in optical design
- Programming skills (Python, Matlab, or Swift)
- Undergraduate degree in physics or engineering

We are looking for motivated people who are not afraid to try new things and step out of their comfort zone while learning modern microscopy techniques and neuroscience. Review of applications begins immediately and will continue until the position is filled.

Research Field

- Optical microscopy
- Fluorescence imaging at video rate
- Optogenetics
- Biophotonics

Research Supervisor

Antoine Godin

Research Environment

CERVO Brain Research Centre

The CERVO Research Center, one of Canada's leading neuroscience and mental health centers, focuses on the root causes of brain diseases. It brings together some sixty researchers in charge of research teams with more than 400 people, offering multidisciplinary expertise, ranging from membrane biophysics to social intervention, and the psychology of cognition.

The CERVO Research Center is devoted to the study of neurosciences and mental health. Its mission is to advance knowledge about the causes and treatment of neurological and psychiatric illnesses by developing new technologies and methodologies to unravel the mysteries of the brain and by continuously linking basic and clinical research.

https://cervo.ulaval.ca/en/about-cervo

Web Site


Financial Aid Available by Program of Study

Doctorate in Biophotonics

Program description

Financial Aid Available*

Financial Aid Related to Research Project

Information unavailable

Program-Specific Financial Aid

Graduate Studies Awards

Milestone Amount
Progression scholarship
7 x $500
Doctoral exam or seminar presentation
$750
Doctoral exam, seminar or conference
$1,000
Publication
$750
Communication
$1,000
First submission of dissertation
$1,000*
Total $8,500

*A $500 bonus will be added to the graduation scholarship if the initial submission is made before the semester preceding the final qualifying semester.

Université Laval: Student Financial Aid

Funding source Amount
Leadership and Comittment Scholarship (Canadians & permanent residents)
$30,000
Citizens of the World Scholarship (International students) $30,000
Mobility Grant for Out-of-Province Internships or Research Visits (in French)
$1,000 to $2,000
Graduate Scholarships from Granting Agencies   
$20,000 to $70,000$
Online Directory of Graduate Scholarships (in French)
$500 to $50,000

Supplemental Tuition Fee Exemption Scholarship Program: Entitles international students to pay Canadian student tuition fees, for overall savings of around $40,000. If you are benefiting of this scholarship program, the doctoral admission scholarship will go toward paying your supplemental tuition fees. You will not receive the $2,000 scholarship amount directly; rather it will be applied over your first two semesters to the supplemental portion of your tuition fees.

* Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.

Doctorate in Neurosciences

Program description

Financial Aid Available*

Financial Aid Related to Research Project

Information unavailable

Program-Specific Financial Aid

Graduate Studies Awards

Milestone Amount
Program progress award (S-1 to S-8)
8 x $525
Program progress award (S-9 to S-11) 3 x $200
Successful completion of Ph.D exam
$800
Submission of dissertation deposit before the end of the 12th semester
$2,000
Language training
$250
Total $7,850

Université Laval: Student Financial Aid

Funding source Amount
Leadership and Comittment Scholarship (Canadians & permanent residents)
$30,000
Citizens of the World Scholarship (International students) $30,000
Mobility Grant for Out-of-Province Internships or Research Visits (in French)
$1,000 to $2,000
Graduate Scholarships from Granting Agencies   
$20,000 to $70,000$
Online Directory of Graduate Scholarships (in French)
$500 to $50,000

Supplemental Tuition Fee Exemption Scholarship Program: Entitles international students to pay Canadian student tuition fees, for overall savings of around $40,000. If you are benefiting of this scholarship program, the doctoral admission scholarship will go toward paying your supplemental tuition fees. You will not receive the $2,000 scholarship amount directly; rather it will be applied over your first two semesters to the supplemental portion of your tuition fees.

* Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.

Master's Degree in Biophotonics with thesis

Program description

Financial Aid Available*

Financial Aid Related to Research Project

Information unavailable

Program-Specific Financial Aid

Graduate Studies Awards

Milestone Amount
Evaluated activity
$650
Achievement scholarship $1,000 
Total $1,650

Université Laval: Student Financial Aid

Sources de financement Montant
Leadership and Comittment Scholarship (Canadians & permanent residents) $10,000
Citizens of the World Scholarship (International students) $20,000
Mobility Grant for Out-of-Province Internships or Research Visits (in French)
$1,000 to $2,000
Graduate Scholarships from Granting Agencies
$17,500 to $40,000
Online Directory of Graduate Scholarships (in French)
$500 to $50,000

* Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.

Master's Degree in Neurosciences with thesis

Program description

Financial Aid Available*

Financial Aid Related to Research Project

Information unavailable

Program-Specific Financial Aid

Graduate Studies Awards

Milestone Amount
First submission of thesis by the end of the 5th semester of full-time registration
$2,000
Language training
$250
Total $2,250

Université Laval: Student Financial Aid

Sources de financement Montant
Leadership and Comittment Scholarship (Canadians & permanent residents) $10,000
Citizens of the World Scholarship (International students) $20,000
Mobility Grant for Out-of-Province Internships or Research Visits (in French)
$1,000 to $2,000
Graduate Scholarships from Granting Agencies
$17,500 to $40,000
Online Directory of Graduate Scholarships (in French)
$500 to $50,000

* Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.

Desired Profile

- Physics
- Physics Engineering

Required Documentation

- Cover letter
- Curriculum vitæ
- Student transcript

Find Out More

Antoine Godin
Professeur adjoint
Département de psychiatrie et de neurosciences
antoine.godin@cervo.ulaval.ca