Abnormal cell division in the development of cancer

Description

To better understand the role of aberrant mitosis in the development of aneuploidy-based diseases such as spontaneous miscarriage and cancer, our lab is interested in understanding the molecular mechanisms and regulation of the mitotic kinases. This project includes studies on protein phospho-regulation and substrate identification, and will involve various molecular and cellular biology approaches including microscopy and mass spectrometry.

Research Field

- Cell Biology
- Molecular Biology
- Mitosis
- Cell Cycle

Research Supervisor

Sabine Elowe

Research Environment

CHU de Québec Research Centre (CRCHU) (CR-NCH site)

The CHU de Québec Research Centre (CRCHU) is part of the CHU de Québec, serving the Québec City region and Eastern Québec. The CHU de Québec is the result of the fusion between the CHUQ and the CHA in July 2012. The CHU de Québec, composed of L'Hôtel-Dieu de Québec and l'Enfant-Jésus Hospital, Saint-François-d'Assise and Saint-Sacrement Hospitals, is the most important healthcare establishment in the province of Québec and one of the largest CHUs in Canada.

Accredited by the the Fonds de recherche du Québec/Santé (FRQS), the CRCHU de Québec is proud to be among the leading health research centres in Canada, employing nearly 2,500 highly qualified people, and over 500 research professionals, under a seven-research axis working in a hospital environment. Nearly 1,000 graduate students, post-graduate interns and fellows frequent the establishment while benefiting from multidisciplinary, international caliber training. The integration of the two original distinct research centres, under the same management, is now complete and has evolved in a very positive way over the last year, enabling the CRCHU de Québec to respond more efficiently to the needs and expectations of the research professionals and partners.

The research teams work at the five hospital sites. The CRCHU de Québec has an agreement with Laval University, making it possible to maintain and develop a pool of expertise and excellence, as well as a training environment for researchers and healthcare professionals in each of the research areas offered. The Centre also works with other research environments and ensures unique and specialized services to the research community, not available elsewhere. Our lab is located at the integrated Cancer centre at the new hospital centre/Hôpital de l'Enfant-Jésus. The CIC is the largest cancer centre in Quebec and one of the largest in Canada.

Web Site

Financial Aid Available by Program of Study

Doctorate in Cellular and Molecular Biology

Program description

Financial Aid Available*

Financial Aid Related to Research Project

$25000 per year for 4 years.

Students are highly encouaged to apply for many of the umérous local (CRCHU), provincial and federal scholarship awards if they are eligible. It represents an excellent way of augmenting the stipend value.

Program-Specific Financial Aid

Graduate Studies Awards

Milestone	Amount
Program progress award (S-1 to S-8)	8 x $525
Program progress award (S-9 to S-11)	3 x $200
Successful completion of Ph.D exam	$800
Submission of dissertation deposit before the end of the 12th semester	$2,000
Language training	$250
Total	$7,850

Université Laval: Student Financial Aid

Funding source	Amount
Leadership and Comittment Scholarship (Canadians & permanent residents)	$30,000
Citizens of the World Scholarship (International students)	$30,000
Mobility Grant for Out-of-Province Internships or Research Visits (in French)	$1,500 to $3,000
Graduate Scholarships from Granting Agencies	$25,000 to $40,000$
Online Directory of Graduate Scholarships (in French)	$500 to $50,000

Supplemental Tuition Fee Exemption Scholarship Program: Entitles international students to pay Canadian student tuition fees, for overall savings of around $49,000.

_{* Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.}

Master's Degree in Cellular and Molecular Biology with thesis

Program description

Financial Aid Available*

Financial Aid Related to Research Project

$23 per year for 2 years.

Program-Specific Financial Aid

Graduate Studies Awards

Milestone	Amount
First submission of thesis by the end of the 5th semester of full-time registration	$2,000
Language training	$250
Total	$2,250

Université Laval: Student Financial Aid

Sources de financement	Montant
Leadership and Comittment Scholarship (Canadians & permanent residents)	$10,000
Citizens of the World Scholarship (International students)	$20,000
Mobility Grant for Out-of-Province Internships or Research Visits (in French)	$1,500 to $3,000
Graduate Scholarships from Granting Agencies	$20,000 to $27,000
Online Directory of Graduate Scholarships (in French)	$500 to $50,000

_{* Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.}

Desired Profile

- Biomedical Science
- Biochemistry
- Biology
- Microbiology

Requirements and Conditions

- Ability to work both independently and as part of a team.
- Excellent communication skills in English (oral, written and comprehension) are essential
- Hard working, flexible and motivated students interested in research are welcome to apply for the position.
- Prior experience with cell biology and molecular biology is an asset, but not necessary.

Required Documentation

- Cover letter
- Curriculum vitæ
- Student transcript

Find Out More

Sabine Elowe
Professeur Titulaire
Centre de recherche du CHU de Québec
sabine.elowe@crchuq.ulaval.ca