Longitudinal Plasma Proteomic Profiling in Aortic Stenosis: Identification of Signatures Associated with Disease Progression and Clinical Outcomes

Description

This projet aims to investigate the proteomics associated with the development and progression of aortic stenosis, a dehenerative heart valve disease. The PROGRESSA clinical study (Study of Metabolic Factors Determining the Progression of Aortic Stenosis) is one of the most extensive clinical studies in the world focused on the progression of AS. Given the large amount of biological material collected to date, a specific study on the proteomics of this disease will be conducted. The selected student will work in collaboration with the teams of Dr Sébastien Thériault (supervisor) and Dr Philippe Pibarot (co-supervisor) to carry out the analyses.

Research Field

- Bioinformatics
- Proteomics
- Valvular heart disease
- Aortic stenosis
- Biological sciences
- Mathematics
- Statistics

Research Supervisors

Philippe Pibarot
Nancy Côté

Research Environment

IUCPQ-ULaval -cardiology research area

Our research center is the only center subsidized by the Fonds de recherche du Québec – Santé (FRQ-S) which brings together research areas in cardiology, pulmonology and obesity/metabolism, three areas considered priorities due to the considerable economic and societal impact of the diseases associated with them.

Web Site

Financial Aid Available by Program of Study

Master's Degree in Biology with thesis

Program description

Financial Aid Available*

Financial Aid Related to Research Project

$25000 per year for 1 year.

Program-Specific Financial Aid

Graduate Studies Awards

Université Laval: Student Financial Aid

Sources de financement	Montant
Leadership and Comittment Scholarship (Canadians & permanent residents)	$10,000
Citizens of the World Scholarship (International students)	$20,000
Mobility Grant for Out-of-Province Internships or Research Visits (in French)	$1,500 to $3,000
Graduate Scholarships from Granting Agencies	$20,000 to $27,000
Online Directory of Graduate Scholarships (in French)	$500 to $50,000

_{* Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.}

Master's Degree in Clinical and Biomedical Sciences with thesis

Program description

Financial Aid Available*

Financial Aid Related to Research Project

$25000 per year for 1 year.

Program-Specific Financial Aid

Graduate Studies Awards

Milestone	Amount
First submission of thesis by the end of the 5th semester of full-time registration	$2,000
Language training	$250
Total	$2,250

Université Laval: Student Financial Aid

Sources de financement	Montant
Leadership and Comittment Scholarship (Canadians & permanent residents)	$10,000
Citizens of the World Scholarship (International students)	$20,000
Mobility Grant for Out-of-Province Internships or Research Visits (in French)	$1,500 to $3,000
Graduate Scholarships from Granting Agencies	$20,000 to $27,000
Online Directory of Graduate Scholarships (in French)	$500 to $50,000

_{* Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.}

Master's Degree in Computer Science with thesis

Program description

Financial Aid Available*

Financial Aid Related to Research Project

$25000 per year for 1 year.

Program-Specific Financial Aid

Graduate Studies Awards

Université Laval: Student Financial Aid

Sources de financement	Montant
Leadership and Comittment Scholarship (Canadians & permanent residents)	$10,000
Citizens of the World Scholarship (International students)	$20,000
Mobility Grant for Out-of-Province Internships or Research Visits (in French)	$1,500 to $3,000
Graduate Scholarships from Granting Agencies	$20,000 to $27,000
Online Directory of Graduate Scholarships (in French)	$500 to $50,000

_{* Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.}

Master's Degree in Mathematics with thesis

Program description

Financial Aid Available*

Financial Aid Related to Research Project

$25000 per year for 1 year.

Program-Specific Financial Aid

Graduate Studies Awards

Université Laval: Student Financial Aid

Sources de financement	Montant
Leadership and Comittment Scholarship (Canadians & permanent residents)	$10,000
Citizens of the World Scholarship (International students)	$20,000
Mobility Grant for Out-of-Province Internships or Research Visits (in French)	$1,500 to $3,000
Graduate Scholarships from Granting Agencies	$20,000 to $27,000
Online Directory of Graduate Scholarships (in French)	$500 to $50,000

_{* Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.}

Master's Degree in Statistics with thesis

Program description

Financial Aid Available*

Financial Aid Related to Research Project

$25000 per year for 1 year.

Program-Specific Financial Aid

Graduate Studies Awards

Université Laval: Student Financial Aid

Sources de financement	Montant
Leadership and Comittment Scholarship (Canadians & permanent residents)	$10,000
Citizens of the World Scholarship (International students)	$20,000
Mobility Grant for Out-of-Province Internships or Research Visits (in French)	$1,500 to $3,000
Graduate Scholarships from Granting Agencies	$20,000 to $27,000
Online Directory of Graduate Scholarships (in French)	$500 to $50,000

_{* Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.}

Desired Profile

- Biomedical Science
- Biochemistry
- Biology
- Computer Software
- Mathematics, Statistics and Actuarial Science
- Bioinformatics
- Statistic
- Microbiology
- Artificial intelligence

Requirements and Conditions

- Hold a B.Sc or M.Sc in bioinformatics or a related field;
- Must have an excellent academic record;
- Must demonstrate motivation, autonomy and rigor, demonstrate dedication to research, initiative and the ability to work as part of a team;
- Process strong organizational skills and be proactive;
- Have oral communication skills in both French and English;
- Knowledge of R software and Linux, as well as experience in statistical analysis are considered assets.

Required Documentation

- Cover letter
- Curriculum vitæ
- Student transcript

Candidates who wish to apply are invited to send the documents listed above to the attention of
Dr Sébastien Thériault at the following e-mail address: nancy.cote@criucpq.ulaval.ca before June 30th, 2026.

Application Deadline

June 30, 2026

Find Out More

Nancy Côté
Chercheur associé et codirecteur de laboratoire
Institut universitaire de cardiologie et de pneumologie de Québec
nancy.cote@criucpq.ulaval.ca